Why is migraine treatment important?
Migraine is a serious condition classified in the ICD-10 as G43. Increasing attention is being paid to the impact of migraines on the body—especially when left untreated. Because frequent attacks can affect not only well-being but also health, it’s important to take care of yourself and consult a specialist about migraine treatment.
Prescription medication for migraines
Migraine is a condition that is not yet fully understood. However, medicine has developed various ways to relieve migraine pain and prevent future episodes.
In reality, every effective migraine medication is prescription-based, meaning you need to consult a doctor before using it. Why? Because these drugs are powerful. Sometimes, opioids—strong prescription medications—are used to treat migraines. While effective in relieving and blocking pain, they may also cause addiction.
Fortunately, you don’t have to figure out how to safely treat migraines on your own. You can consult a doctor via Dimedic.eu, where a physician can prescribe tryptans and ergot alkaloid derivatives—drugs that effectively relieve pain without addiction risks. If you're a returning Dimedic patient renewing a prescription for the same medication, the doctor will make the decision without contacting you. If it's your first time starting treatment, the doctor will call to perform an evaluation.
Some medications used prophylactically for migraines are originally intended for treating high blood pressure or epilepsy—they can reduce migraine frequency and improve quality of life.
In cases of frequent migraines, prescription medications like beta-blockers also work well. Beta-blockers block beta-adrenergic receptors and are prescribed for migraine relief.
Antidepressants (both older tricyclic and newer serotonin reuptake inhibitors) are also effective.
The appropriate treatment is prescribed by a doctor, based on a detailed medical interview and any available test results.
Prescription migraine medications – types of drugs
Migraine medications can be categorized by generation:
Older-generation migraine tablets – Prescription medications used for acute migraine treatment. These include ergot alkaloid derivatives that block α-adrenergic vascular receptors, causing blood vessel constriction in the head and reducing pain. Though effective, they are less commonly used due to side effects like nausea, vomiting, blood pressure fluctuations, numbness, and muscle cramps. Examples include: Ergotamine, Dihydroergotamine, Dihydroergotoxin. Available as tablets, suppositories, or nasal sprays.
New-generation prescription medications – These are tryptans, selective 5-HT1B/D receptor agonists that cause blood vessel constriction and reduce neurovascular inflammation. Tryptans include: sumatriptan (e.g., Sumamigren, Imigran), zolmitriptan (e.g., Zolmiles), eletriptan, naratriptan, and frovatriptan. Forms include oral tablets, sublingual tablets, suppositories, nasal sprays, and injections.
Opioids – Very strong painkillers prescribed only when other medications fail. Examples: codeine, tramadol (weaker); morphine, fentanyl, heroin (stronger). Though effective, opioids carry addiction risk and may increase pain sensitivity over time. Therefore, they are a last resort.
Over-the-counter migraine tablets
While prescription drugs are best for severe migraine attacks, over-the-counter painkillers can be effective for mild to moderate migraines.
OTC migraine medications include NSAIDs (non-steroidal anti-inflammatory drugs):
Acetylsalicylic acid (aspirin)
Ibuprofen
Naproxen
Diclofenac
Ketoprofen
Paracetamol
These drugs work by inhibiting cyclooxygenase (COX), an enzyme that promotes inflammation, thus reducing symptoms. NSAIDs usually provide pain relief within 30 minutes and last about 6 hours. Paracetamol works similarly, is gentler on the body, and can be used during pregnancy and breastfeeding—its effect begins around 1 hour after intake and lasts 5–6 hours.
You can also buy OTC migraine tablets with caffeine. Caffeine isn’t a migraine drug itself, but it enhances the effects of other medications like paracetamol or ergotamine. However, long-term use is not recommended, as the body builds tolerance and migraine episodes may require higher doses.
Medical support for migraines is essential!
Now that you know what helps with migraines and that effective treatment involves prescription medications, don’t hesitate to seek professional help to avoid complications.
If you don’t want or don’t have time for an in-person visit, use an online consultation through Dimedic.eu. The doctor will assess your needs and recommend the best treatment based on your symptoms and expectations. If you're a returning Dimedic patient, the doctor may renew your prescription without direct contact. For new treatment plans, the doctor will call to perform a consultation.